Medical Marijuana: Benefit or Slippery Slope?

Author:  R. Alan Harrop, Ph.D

Well, here we go again. The N.C. General Assembly may be considering making marijuana legal for medical use, which they declined to approve in the last session. Apparently enough people in North Carolina (or at least in the General Assembly) are pushing this idea so that it keeps coming up. Let’s take a look at the pros and cons of medical marijuana. It should be noted that medical marijuana is legal in 38 states and the District of Columbia.

There is surprisingly little valid scientific research on the health benefits of marijuana. Most of what is claimed is based on anecdotal reports or small studies on short term benefits. Some of the claims are that it relieves nausea caused by some cancer treatments, relief of chronic pain, although not severe pain such as from surgery or broken bones, epilepsy and seizures, Alzheimer disease symptoms, HIV/Aids, and Crohn’s disease. Marijuana has over 100 different chemicals, so it is difficult to isolate the beneficial elements for each disorder. CBD is alleged to have positive effects on health while THC produces the euphoria or high that people experience. It should also be noted that marijuana is used to treat the symptoms of a medical condition, not the cause of that condition. Another important issue is whether there already exist legal drugs or treatments that patients can readily access that address these symptoms.

There are also negative effects. Because marijuana is a mind altering substance, changed perception and reaction times can negatively affect things like driving, leading to more injuries and deaths. Children can be especially harmed if they access marijuana, particularly ingestible forms such as gummy bears, cookies, brownies, etc. Although the long term impacts are not clearly understood, cognitive thinking ability and memory declines are documented for all ages. Confusion, poor muscle coordination, and dizziness are common. Motivation to lead a rewarding traditional life of work, family, and associated rewards often deteriorates, leading to nonproductive citizens. No society can flourish with large numbers of citizens addicted to drugs. Of course, the euphoria induced by marijuana is strongly related to its addictive potential and especially to its role as a gateway drug that leads the user to more potent drugs such as meth or heroin. Having worked in the N.C. Department of Correction as the Mental Health Services Director, I can testify to the numerous cases of criminal behavior in pursuit of illegal drugs that started with smoking marijuana. Interestingly, the FDA has not approved marijuana for general medical use except lab produced Epidiolex, Marinol and Cesamet to treat nausea and vomiting from chemotherapy, and low appetite for HIV patients.

Recent reports of the dramatic increase of China’s role in the marijuana trade adds another risk that should concern us all. There is increasing evidence that Chinese invaders are controlling the production and distribution of marijuana from California to Maine. They grow it and distribute it throughout the country, relying on the increased flow of illegal Chinese over our southern border for laborers. The Chinese are also the originators of the fentanyl crisis that is killing somewhere near 100,000 Americans each year. Now what could possibly go wrong with our biggest adversary, China, controlling marijuana and fentanyl production which can produce a deadly combination? Are we on a path of self-destruction? It makes one wonder. Twenty four states that started with medical marijuana have now legalized its recreational use. Result: 20% of the US population now report using marijuana. So if you think using marijuana is a good thing, then support medical marijuana since that is what is most likely to occur. Personally, I do not.

Wonderful News From Israel

On October 26th, The Times of Israel posted a story about a breakthrough in cancer research that has occurred in Israel.

The article reports:

“Our interim results in a major study of patients with leukemia shows that our system yields the maximum efficiency from chemo, with a minimum of toxicity,” said Dr. Ruth Ben Yakar, CEO of BioSight. “Our method of using chemo does not cause brain damage or weaken blood cells,” with all its attendant phenomena, such as lethargy, loss of hair, etc.

BioSight’s “Trojan horse” chemo technology doesn’t only work for leukemia patients, said Ben Yakar. “We believe it will be effective in many other kinds of cancer as well. It’s a matter of finding the amino acid that a specific cancer is ‘allergic’ to, and packaging it in a structure that the cancer cell thinks contains material that strengthens it, while in reality it contains material that destroys it.”

I am sure everyone reading this has watched someone they love go through the agonies of chemotherapy because that was the only hope of survival. It would be wonderful if this procedure can cure cancer without doing major harm to the patient.

The article further reports:

While further tests are needed, Ben Yakar is very optimistic that the technology – which, she said, could be applied to other cancers as well — will receive recognition as a Breakthrough Therapy, able to treat patients who have no other medical recourse.

“We are excited with the results obtained to date with treatment of AML and ALL patients with Astarabine,” said Ben Yakar. “These patients would have otherwise had very limited treatment options. We are optimistic that Astarabine could bring real hope to many patients and an answer to unmet needs in the treatment of hematologic malignancies.”

This is fantastic news.