When Politics Overrides Science

Yesterday Just the News posted an article about some recent statements by Harvey Risch, a professor of epidemiology at Yale and director of that school’s Molecular Cancer Epidemiology Laboratory.

The article reports:

Harvey Risch, a professor of epidemiology at Yale as well as the director of that school’s Molecular Cancer Epidemiology Laboratory, argues in a Newsweek op-ed this week that “the data fully support” the wide use of hydroxychloroquine as an effective treatment of COVID-19. 

“When this inexpensive oral medication is given very early in the course of illness, before the virus has had time to multiply beyond control, it has shown to be highly effective,” Risch argues in the column. 

…Risch, at Newsweek, argues that multiple studies over the past several months have demonstrated that the drug is a safe and efficacious treatment method for COVID-19.

Among the successful treatment experiments, he writes, are “an additional 400 high-risk patients treated by Dr. Vladimir Zelenko, with zero deaths; four studies totaling almost 500 high-risk patients treated in nursing homes and clinics across the U.S., with no deaths; a controlled trial of more than 700 high-risk patients in Brazil, with significantly reduced risk of hospitalization and two deaths among 334 patients treated with hydroxychloroquine; and another study of 398 matched patients in France, also with significantly reduced hospitalization risk.”

The media’s portrayal of this drug (which was approved for medical use in the United States in 1955 has been commonly used to treat arthritis, lupus, and certain types of malaria) has been almost entirely negative. It should be noted that the drug costs about 60¢ a pill. Some of the other drugs pharmacy companies are recommending to treat the coronavirus cost as much as $6,000 a pill. You don’t suppose there might be a financial as well as a political aspect to the objections to hydroxychloroquine.

The article concludes:

Risch says the drug is most effective “when given very early in the course of illness, before the virus has had time to multiply beyond control.”

Though according to Risch the benefits of the drug are clear, he nevertheless concedes that the subject “has become highly politicized.”

“For many, it is viewed as a marker of political identity, on both sides of the political spectrum,” he said. “Nobody needs me to remind them that this is not how medicine should proceed.”

He also argues that “the drug has not been used properly in many studies,” and that delays in administering the drug have reduced its effectiveness. 

“In the future,” Risch says in the column, “I believe this misbegotten episode regarding hydroxychloroquine will be studied by sociologists of medicine as a classic example of how extra-scientific factors overrode clear-cut medical evidence.”

“But for now,” he adds, “reality demands a clear, scientific eye on the evidence and where it points.”

Some objectivity on the part of the media would be nice.